The Centers for Disease Control and Prevention estimates that influenza causes 9 million to 45 million illness each year. 'We look forward to advancing our core modality of prophylactic mRNA vaccines so that we can continue to make an impact on global public health.' 'Our vision is to develop an mRNA combination vaccine so that people can get one shot each fall for high efficacy protection against the most problematic respiratory viruses,' Bancel said in a statement. Moderna CEO Stéphane Bancel said the pharmaceutical company hopes to eventually create vaccines that can target multiple viruses, including the flu, RSV and COVID-19, in one shot. And Pfizer and BioNTech first announced plans for such a shot in 2018. Sanofi and Translate Bio previously had begun clinical trials on an mRNA flu vaccine. Moderna announced Wednesday that it had begun dosing volunteers in a study of a potential mRNA flu vaccine. That way, the vaccine would be a better match, improving its efficacy. And the vaccines usually are only 40-60% effective because scientists have to make an educated guess about which flu strains will be the most dominant in the upcoming season.Īn mRNA vaccine, on the other hand, can be developed less than a month after the genetic sequence of a new flu strain is identified, The Verge reported.Īnd since mRNA vaccines use synthetically-produced genetic material rather than live viruses, scientists say they could wait to identify the most dominant flu strains before developing the vaccine each year.

The resulting proteins trigger the body's immune response when the vaccine is administered.īut it can take up to six months to develop each year's vaccine. The viruses are then killed or inactivated. In the COVID-19 vaccines, the mRNA instructs cells to make copies of the coronavirus's distinctive spike protein, triggering an immune response without any direct contact with the virus.īy contrast, most flu shots are developed by growing influenza viruses in mammalian cells or chicken eggs. Is modern hygiene bad for childhood immunity? New research says no.

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With the shots successfully reducing the risk of illness, researchers now are considering applying it to the fight against other viruses, including influenza. The COVID-19 vaccines produced by Pfizer and Moderna utilize synthetic messenger RNA, a technology that was considered experimental prior to the pandemic.

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